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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPA2 All Species: 3.64
Human Site: S317 Identified Species: 5.71
UniProt: Q9H2U2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2U2 NP_001029363.1 334 37920 S317 L V E S V S S S P N K E S N E
Chimpanzee Pan troglodytes XP_001164495 327 36742 P307 I V D A L P P P C E S A C T V
Rhesus Macaque Macaca mulatta XP_001082969 325 36595 S313 E A R S L V E S P C C A L P P
Dog Lupus familis XP_535679 303 34598 S291 S S S P N Q E S N T E D Q V W
Cat Felis silvestris
Mouse Mus musculus Q91VM9 330 38096 P312 L V E S V P T P S M N K E S N
Rat Rattus norvegicus NP_001129343 330 37824 P312 L V E S I P T P S M S K E S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420502 467 51453 P447 I V Q S A P V P A N G D S V C
Frog Xenopus laevis NP_001084935 304 34676 V292 S P G S P N K V T A D V D T W
Zebra Danio Brachydanio rerio NP_001017833 291 32624 P279 C G D A S P I P T S V D K W F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O77460 338 37921 G319 I L A E A P D G G Q V E E V S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18680 407 44134 H389 A I G A T P E H G A N A P L P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays O48556 214 24351 D202 E A I Q Y S M D L Y A Q Y I L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXC9 300 33362 V288 N E S W A K L V K R S V D A G
Baker's Yeast Sacchar. cerevisiae P00817 287 32281 K275 K A D A P I D K S I D K W F F
Red Bread Mold Neurospora crassa Q6MVH7 290 32621 S278 P P A P I D S S I D K W F F I
Conservation
Percent
Protein Identity: 100 50.9 91.3 78.1 N.A. 75.4 73.6 N.A. N.A. 47.5 57.1 54.4 N.A. 45.2 N.A. 38.3 N.A.
Protein Similarity: 100 67 92.8 84.7 N.A. 84.1 83.5 N.A. N.A. 56.9 72.1 67.9 N.A. 60.9 N.A. 52.8 N.A.
P-Site Identity: 100 6.6 20 6.6 N.A. 33.3 26.6 N.A. N.A. 26.6 6.6 0 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 33.3 26.6 20 N.A. 53.3 53.3 N.A. N.A. 46.6 13.3 26.6 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. 23.3 N.A. 34.4 44.6 42.2
Protein Similarity: N.A. 40.4 N.A. 50 58.3 58
P-Site Identity: N.A. 6.6 N.A. 0 0 20
P-Site Similarity: N.A. 13.3 N.A. 0 20 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 20 14 27 20 0 0 0 7 14 7 20 0 7 0 % A
% Cys: 7 0 0 0 0 0 0 0 7 7 7 0 7 0 7 % C
% Asp: 0 0 20 0 0 7 14 7 0 7 14 20 14 0 0 % D
% Glu: 14 7 20 7 0 0 20 0 0 7 7 14 20 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 14 14 % F
% Gly: 0 7 14 0 0 0 0 7 14 0 7 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 20 7 7 0 14 7 7 0 7 7 0 0 0 7 7 % I
% Lys: 7 0 0 0 0 7 7 7 7 0 14 20 7 0 0 % K
% Leu: 20 7 0 0 14 0 7 0 7 0 0 0 7 7 7 % L
% Met: 0 0 0 0 0 0 7 0 0 14 0 0 0 0 0 % M
% Asn: 7 0 0 0 7 7 0 0 7 14 14 0 0 7 7 % N
% Pro: 7 14 0 14 14 47 7 34 14 0 0 0 7 7 14 % P
% Gln: 0 0 7 7 0 7 0 0 0 7 0 7 7 0 0 % Q
% Arg: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % R
% Ser: 14 7 14 40 7 14 14 27 20 7 20 0 14 14 14 % S
% Thr: 0 0 0 0 7 0 14 0 14 7 0 0 0 14 0 % T
% Val: 0 34 0 0 14 7 7 14 0 0 14 14 0 20 7 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 7 7 7 14 % W
% Tyr: 0 0 0 0 7 0 0 0 0 7 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _